Medicine
15 patents
X-Ray Tube
Coolidge's General Electric tube, patents from 1913, used hot tungsten cathodes for steady, controllable X-ray output. Earlier gas...
Insulin
Toronto's team isolated insulin in 1921 and patented it in 1923 for one dollar each, licensing royalty-free to universities and El...
Streptomycin
Rutgers graduate student Schatz discovered streptomycin in soil bacteria screening run by Waksman, who patented it and licensed ro...
Oral Contraceptive
Djerassi's Mexico City Syntex team synthesized norethisterone from yams in 1951, patents following through 1956 as Searle and Pinc...
Implantable Pacemaker
Greatbatch grabbed the wrong resistor in 1956 and watched his oscillator tick at heartbeat pace. His mercury-powered implant, pate...
CT Scanner
EMI's Hounsfield, funded partly by Beatles record profits, patented computed tomography from 1968 and scanned a patient's head in ...
MRI Scanner
Damadian's 1971 tumor-detection finding and 1974 patent on scanning apparatus, field-focused by his Fonar company, launched magnet...
Monoclonal Antibodies
Cambridge's Kohler and Milstein fused myeloma cells with B-cells, making immortal antibody factories of single specificity. The 19...
Balloon-Expandable Stent
Palmaz, an Argentine radiologist, hand-etched his wire-mesh tube and partnered with cardiologist Richard Schatz; Johnson and Johns...
mRNA Vaccine Platform
Kariko and Weissman's 2005 discovery that pseudouridine-substituted mRNA dodges immune attack, patented through UPenn as 8,278,036...
CRISPR Gene Editing
Doudna and Charpentier's 2012 Science paper on Cas9 programming met Zhang's Broad Institute eukaryotic-editing filings, granted sp...
Polio Vaccine
Jonas Salk's inactivated polio vaccine was tested on well over a million American children in 1954, one of the largest medical tri...
Polymerase Chain Reaction
Kary Mullis conceived the polymerase chain reaction in 1983 while driving through the California hills at night. Repeated cycles o...
OncoMouse
Harvard geneticists Philip Leder and Timothy Stewart created a mouse carrying an activated cancer gene, making it highly susceptib...
BRCA Gene Patents
After the BRCA1 and BRCA2 genes linked to hereditary breast and ovarian cancer were identified in the mid-1990s, Myriad Genetics o...