CRISPR Gene Editing

Feng Zhang, Broad Institute, USA, patent 8,697,359 of 2014. The editing fight between two legendary teams.

Overview

Doudna and Charpentier's 2012 Science paper on Cas9 programming met Zhang's Broad Institute eukaryotic-editing filings, granted speedily 2014 and 2015. The US interference fight ended 2022 with both keeping their claims by technicality; Europe revoked Broad's in parallel disputes. Editing has cured sickle-cell patients via approved Casgevy therapy. Doudna and Charpentier took the 2020 chemistry Nobel. Zhang's patents anchor the commercial toolkit; the lawyers are still eating well.